科研之友
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摘要
Background: Although Chinese form the largest non-English speaking group in Australia, cardiovascular disease (CVD) risk profiles among Chinese Australians have not been comprehensively examined, nor has the effect of mixed-Chinese ethnicity been adequately explored. This study is to investigate cardiovascular risk among Chinese, mixed-Chinese, and non-Chinese Australians. Methods: Using data from 266,696 Australian participants from the 45 and Up Study (2006-2009), this study investigated cardiovascular risk among Chinese (n = 3454), mixed-Chinese (n = 1062), and non-Chinese (n = 262,180) participants. Poisson regression models with a robust error variance were used to estimate prevalence ratio (PR) and 95% confidence intervals (CI) for CVD (coronary heart disease (CHD) and stroke) and six major risk factors (hypertension, diabetes, high cholesterol, smoking, overweight/obesity, and physical inactivity) by ethnicity using non-Chinese participants as the reference group. Each outcome was adjusted for sociodemographic characteristics. Results: Compared with non-Chinese Australians, Chinese had lower prevalence of CHD (PR 0.67; 95% CI 0.59-0.75) and stroke (PR 0.67; 95% CI 0.51-038). Of the risk factors, Chinese had higher prevalence of diabetes (PR 1.25; 95% CI 1.12-1.39), smoking (PR 1.22; 95% CI 1.04-1.43) and physical inactivity (PR 1.48; 95% CI 1.41-1.55) but lower prevalence of hypertension (PR 0.90; 95% CI 0.86-0.95), high cholesterol (PR 0.87; 95% CI 0.79-0.95), and overweight/obesity (PR 0.46; 95% CI 0.43-0.48). Mixed-Chinese had higher prevalence of CVD and worse CVD risk profiles compared with Chinese. Conclusions: There are marked differences in the prevalence of CVD and risk factors among three groups. The noticeable variations in CVD risk between Chinese and mixed-Chinese indicate that conventional classification of treating all Chinese as homogeneous could be misleading. More investigation into the health outcomes of mixed ancestry is warranted.
- 出版日期2017-1-15
