A colorimetric and ratiometric fluorescent probe for detection of palladium in the red light region

作者：Xiang, Kaiqiang; Liu, Yunchang; Li, Changjiang; Tian, Baozhu^*; Zhang, Jinlong

来源：RSC Advances, 2015, 5(65): 52516-52521.

DOI：10.1039/c5ra06144j

• CONFIGURATIONALLY LOCKED POLYENE
• HYDROGEN-SULFIDE
• IN-VIVO
• SELECTIVE DETECTION
• IMAGING PALLADIUM
• CHEMOSENSOR
• SHIFT
• EMISSION
• SENSOR
• NAPHTHALIMIDE

Developing probes for selective and sensitive detection of palladium in living organisms is of great importance. In this work, we synthesized a colorimetric and ratiometric fluorescent probe (Probe 1) with red light emission (lambda(em) = 643 nm) by employing an isophorone based fluorescent dye as the fluorophore and an allylcarbamate group as the response unit. Based on the Pd-0-triggered cleavage reaction, Probe 1 showed high response speed, selectivity, and sensitivity towards palladium species. Upon addition of palladium, the absorption and emission spectra of Probe 1 exhibited obvious red-shifts, which can be easily discriminated by the naked eye. In terms of palladium, the detection limit is as low as 24.2 nM and the signal-to-noise ratio in fluorescence intensity can reach 85-fold. As a red emitting ratiometric sensor, Probe 1 can be potentially used for quantitative detection of palladium in living organisms.

• 出版日期2015
• 单位华东理工大学