A new superoxide-generation inhibitor from rhizome of Anemone raddeana Regel

作者：Lu Jin Cai^*; Xu Bei Bei; Gao Song; Kodama Hiroyuki

来源：Chinese Chemical Letters, 2009, 20(6): 694-697.

DOI：10.1016/j.cclet.2008.12.037

• Anemone raddeana Regel
• Raddeanoside R(19)
• Superoxide generation-inhibitor

A new triterpenoid saponins, raddeanoside R(19) (1) was isolated from the rhizome of Anemone raddeana Regel. The effects of raddeanoside R(19) on superoxide generation in human neutrophil were evaluated. The compound suppressed the superoxide generation induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP), phorbol 12-myristate 13-acetate (PMA) and arachidonic acid (AA) in a different concentration-dependent manner.

• 出版日期2009-6
• 单位沈阳药科大学