Artificial metalloenzymes for olefin metathesis based on the biotin-(strept)avidin technology

作者:Lo Cheikh; Ringenberg Mark R; Gnandt David; Wilson Yvonne; Ward Thomas R*
来源:Chemical Communications, 2011, 47(44): 12065-12067.
DOI:10.1039/c1cc15004a

摘要

Incorporation of a biotinylated Hoveyda-Grubbs catalyst within (strept) avidin affords artificial metalloenzymes for the ring-closing metathesis of N-tosyl diallylamine in aqueous solution. Optimization of the performance can be achieved either by chemical or genetic means.

  • 出版日期2011