Decarboxylation of 5-amino-orotic acid and a Schiff base derivative by rhenium(V)

作者：Mukiza J; Gerber T I A^*; Hosten E C

来源：Inorganic Chemistry Communications, 2015, 57: 54-57.

DOI：10.1016/j.inoche.2015.04.024

• Decarboxylation
• Rhenium(V)
• 5-Amino-orotic acid
• X-ray crystal structures

The reaction of 5-amino-orotic acid (H(2)aor) with trans-[ReOBr3(PPh3)(2)] in 2-propanol produced the complex [Re-V(apd)Br(aor)(PPh3)(2)] (1, apd(2-) = 5-imidopyrimidine-2,4-dione). The ligand apd(2-) was formed by the decarboxylation of H(2)aor, and it is coordinated via the dinegative imido nitrogen only. The Schiff base derivative of H(2)aor, salicylimine-orotic acid {5-(2-hydroxy-benzylideneamino)-1,2,3,6-tetrahydro-2,6-dioxopyrimidine4-carboxylic acid; H(2)sor}, was also decarboxylated in the reaction with trans-[ReOl (2)(OEt)(PPh3)(2)] in ethanol to form [Re-III(cor)I(PPh3)(2)]l (2, Hcor = 5-(2-hydroxybenzylideneamino)-pyrimidine-2,4(1H,3H)-dione). Decarboxylation of H(2)sor was not observed in its reaction with trans-[ReOCl3(PPh3)(2)], which led to the isolation of [ReOCl(sor)(PPh3)] (3), in which sor(2-) is coordinated as a tridentate ligand as expected. Spectroscopic results and the X-ray-crystal structures of compounds 1-3 are also presented.

• 出版日期2015-7