Delayed Gastric Emptying Accelerates Pancreatic Anastomotic Stricture Formation after Pancreaticogastrostomy for Soft Pancreas

作者：Oida Takatsugu^*; Kano Hisao; Mimatsu Kenji; Kawasaki Atsushi; Kuboi Youichi; Fukino Nobutada; Kida Kazutoshi; Amano Sadao

来源：Hepato-Gastroenterology, 2011, 58(112): 2121-2123.

DOI：10.5754/hge09562

• Pancreatic duct patency
• Pancreaticoduodenectomy
• Pancreaticogastrostomy
• Delayed gastric emptying
• Soft pancreas

Background/Aims: Pancreatic duct dilatation induced anastomotic stenosis of the pancreatic duct is frequently observed in patients who have undergone pancreaticoduodenectomy (PD) with pancreaticogastrostomy (PG). Patency of the pancreaticoenteric anastomosis is one of the most important factors affecting the function of the remnant pancreas and quality of life. Anastomotic stenosis after PG is observed in some patients after approximately 1 to 2 postoperative weeks and is attributed to acute inflammation and fibrosis around the anastomosis. We therefore evaluated the early postoperative changes in remnant pancreatic duct diameter after PG in patients with soft pancreas in terms of delayed gastric emptying (DGE). Methodology: We retrospectively studied 42 patients with soft pancreas who underwent PD with PG. They were divided into 2 groups depending on the grade of DGE; without or slightly DGE group (WS group) and moderate or severe DGE group (MS group). Results: The mean diameter of the pancreatic duct of the remnant pancreas was significantly smaller in the WS group than in the MS group. Conclusions: DGE accelerates pancreatic anastomotic stricture development after PG in patients having soft pancreas with a pancreatic duct with a small diameter. Hence, to maintain the pancreatic duct patency, preventing DGE is important.

• 出版日期2011-12