Distribution and antifungal susceptibility of Candida clinical isolations coming from six health care centers in the metropolitan area of Caracas, Venezuela (years 2003-2005)

作者：Dolande Franco Maribel E; Reviakina Vera; Mercedes Panizo Maria; Macero Carolina; Moren Xiomara; Calvo Alberto; Selgrad Sofia; Papatzikos Juana; Vergara Vivian; Jose Mendoza Maria

来源：Revista Iberoamericana de Micologia, 2008, 25(1): 17-21.

• antifungals
• candidiasis
• epidemiology
• invasive fungal infection
• susceptibility

The aim of this study was to investigate the frequency and antifungal susceptibility of Candida clinical isolations coming from patients with candidiasis in six health care centers of Caracas, Venezuela metropolitan area. The laboratory reports were retrospectively revised from January 2003 through August 2005. The isolated yeasts identification was carried out by conventional methods and antifungal susceptibility was evaluated by ATB-fungus (bioMerieux, France) and Etest (AB Biodisk, Solna, Sweden). One thousand nine hundred seventy seven (1,977) yeasts were studied and their susceptibility testing were carried out only in 1,414 of them. C. albicans was the most isolated yeast (46.7%) and none-albicans Candida-species represented more than half of the isolations (53.4%). All the isolated yeasts evaluated presented CMls <1 mu g/ml to anfotericina B and showed variable susceptibility percentages to fluconazole (91.5%), itraconazole (80%) and voriconazole (98.6%).

• 出版日期2008-3-31
• 单位河北医科大学