Antifungal activity of toothpastes against oral Candida isolates

作者：Yigit N^*; Aktas E; Ayyildiz A

来源：Journal de Mycologie Medicale, 2008, 18(3): 141-146.

DOI：10.1016/j.mycmed.2008.06.003

• toothpastes
• antifungal activity
• Candida

Many types of toothpaste have been formulated over recent years to contain antimicrobial compounds with the aim of preventing or reducing plaque, calculus, gingivial inflammation or dental caries. Different brands have their own composition and concentration of ingredients for their efficacy. In this study, the anticandidal activity of six different toothpastes containing the following active ingredients: sodium fluoride, sodium monofluorophosphate, triclosan and herbal compounds were investigated against eight Candida species [Candida glabrata (n = 35), Candida albicans (n = 25), Candida krusei (n = 10), Candida tropicalis (n = 9), Candida pseudotropicalis (n = 7), Geotrichum candidum (n = 7), Candida lipolytica (n = 5), and Candida lusitaniae (n = 4)], isolated from oral cavities and denture using the agar-diffusion test. Five toothpastes were effective in inhibiting the growth of at Candida species, white one toothpaste was not effective against C. tropicalis, C. pseudo tropical is and C. lusitaniae. The herbal toothpaste exhibited good antifungal activity against all Candida species.

• 出版日期2008-9