A novel quinoline-derived fluorescent "turn-on" probe for Cu2+ with highly selectivity and sensitivity and its application in cell imaging

作者：Wang, Peng; Fu, Jiaxin; Yao, Kun; Chang, Yongxin; Xu, Kuoxi^*; Xu, Yuanqing^*

来源：Sensors and Actuators B: Chemical , 2018, 273: 1070-1076.

DOI：10.1016/j.snb.2018.07.028

• Schiff base
• Fluorescent probe
• Turn on detection
• Cu(2+)ion
• Naked-eye

We have developed a novel quinoline-derived Schiff base fluorescent Cu2+ ion probe fluorescent probe 2-(2hydroxybenzylidene)hydrazono)methyl)- quinolin-8-ol (QH). The probe QH showed a highly selective and sensitive detection of Cu2+ with significant fluorescence "turn-on" response and the solution color changed from colorless to yellowish green. The results of fluorescence titration, Job's plot and HAMS analysis suggested that the stoichiometry of probe QH and Cu2+ was found to be 1:1. The detection limit was found to be 8.08 x 10(-9) M, which far lower than the maximum allowable level of the U.S. Environmental Protection Agency limit (20 M) for drinking water. The bonding mechanism has been discussed according to FT-IR and DFT calculations. Furthermore, probe QH has been successfully applied to living cell imaging.

• 出版日期2018-11-10
• 单位河南大学