Association of Blood Pressure and Hypertension with Alcohol Consumption in HIV-Infected White and Nonwhite Patients

作者：Ikeda Maria Leticia R; Barcellos Nemora T; Alencastro Paulo R; Wolff Fernando H; Brandao Ajacio B M; Fuchs Flavio D; Fuchs Sandra C^*

来源：The Scientific World Journal, 2013, 2013: 169825.

DOI：10.1155/2013/169825

Introduction. Although alcohol abuse is associated with hypertension in whites and nonwhites, it has been scarcely investigated in HIV-infected patients. Objective. To investigate whether the association of alcohol abuse with hypertension is influenced by skin color in HIV-infected individuals. Methods. Cross-sectional study in HIV-infected individuals aged 18 years or older. Demographic characteristics, lifestyle, and HIV infection were investigated. Alcohol abuse was defined as >= 15 (women) and >= 30 g/alcohol/day (men), and binge drinking by the intake of >= 5 drinks on a single occasion. Hypertension was defined by blood pressure >= 140/90 mmHg or use of blood pressure-lowering agents. Results. We studied 1,240 individuals, with 39.1 +/- 10 years, 51% males and 57% whites. Age and body mass index were associated with blood pressure, and there was an independent association of alcohol abuse with hypertension in whites (RR = 1.9, 95% CI 1.1-3.3) and nonwhites (RR = 2.4, 95% CI 1.4 to 4.0). Among nonwhite individuals who were alcohol abusers, systolic (9.3 +/- 3.2; P = 0.001) and diastolic blood pressures (6.4 +/- 2.1;P = 0.008) were higher than in nonabusers. Conclusion. Alcohol abuse is a risk factor for hypertension in white and nonwhite HIV-infected individuals. The association of ethanol consumption with blood pressure is not explained by AIDS-related conditions.

• 出版日期2013