A new diphenolic metabolite isolated from the marine-derived fungus Aspergillus niger 102

作者:Zhang, Pan Pan; Song, Shuang; Lang, Jia Jia; Jia, Chun Xiu; Yan, Su Jun; Liu, Lan; Chen, Sen Hua*; Li, Jing*
来源:Journal of Asian Natural Products Research, 2019, 21(8): 813-819.
DOI:10.1080/10286020.2018.1488830

摘要

A new diphenolic derivative asperdiphenol A (1), along with nine known compounds (2-10), was isolated from the marine-derived fungus Aspergillus niger 102. Their structures were elucidated on the basis of spectroscopic analysis including NMR and MS spectrometry. Compound 1 was suggested to be a chiral mixture by the specific rotation and chiral HPLC. Compound 1 was evaluated for its anti-inflammatory, antibacterial, and cytotoxic activity. [GRAPHICS] .