A novel fluorescence probe based on triphenylamine Schiff base for bioimaging and responding to pH and Fe3+

作者：Wang, Lei; Yang, Xiaodong; Chen, Xiuli; Zhou, Yuping; Lu, Xiaodan; Yan, Chenggong; Xu, Yikai; Liu, Ruiyuan^*; Qu, Jinqing^*

来源：Materials Science & Engineering C-Materials for Biological Applications, 2017, 72: 551-557.

DOI：10.1016/j.msec.2016.11.108

• Fluorescence probe
• Triphenylamine
• Bioimaging
• Schiff base

A novel fluorescence probe 1 based on triphenylamine was synthesized and characterized by NMR, IR, high resolution mass spectrometry and elemental analysis. Its fluorescence was quenched when pH below 2. There was a linear relationship between the fluorescence intensity and pH value ranged from 2 to 7. And its fluorescence emission was reversibility in acidic and alkaline solution. Furthermore, it exhibited remarkable selectivity and high sensitivity to Fe3+ and was able to detect Fe3+ in aqueous solution with low detection limit of 0.511 mu M. Job plot showed that the binding stoichiometry of 1 with Fe3+ was 1:1. Further observations of H-1 NMR titration suggested that coordination interaction between Fe3+ and nitrogen atom on C=N bond promoted the intramolecular charge transfer (ICT) or energy transfer process causing fluorescence quenching. Additionally, 1 was also able to be applied for detecting Fe3+ in living cell and bioimaging.

• 出版日期2017-3-1
• 单位华南理工大学; 南方医科大学