Asthma morbidity and treatment in children with sickle cell disease

作者：Anim Samuel O; Strunk Robert C; DeBaun Michael R^*

来源：Expert Review of Respiratory Medicine, 2011, 5(5): 635-645.

DOI：10.1586/ERS.11.64

• acute chest syndrome
• asthma
• bronchial hyper-reactivity
• bronchodilator response
• pulmonary function tests
• sickle cell disease
• sickle cell pain

Expert Rev. Respir. Med. 5(5), 635-645 (2011) Children with sickle cell disease (SCD) and a comorbid condition of asthma have increased numbers of vaso-occlusive pain and acute chest syndrome episodes, and all-cause mortality. When assessed systematically, asthma prevalence is probably similar among children with SCD when compared with the general African American population. With increasing recognition of the importance of asthma in the management of SCD, hematologists must become familiar with asthma and develop a multidisciplinary approach, including early recognition, appropriate management and referral to asthma specialists.

• 出版日期2011-10