A new polyphosphate calcium material with morphogenetic activity

作者:Mueller Werner E G; Tolba Emad; Schroeder Heinz C; Wang Shunfeng; Glasser Gunnar; Munoz Espi Rafael; Link Thorben; Wang Xiaohong
来源:Materials Letters, 2015, 148: 163-166.
DOI:10.1016/j.matlet.2015.02.070

摘要

Polyphosphate [polyP] has been proven to elicit morphogenetic activity on bone cells. By applying mild reaction conditions, a Ca-polyP material that displays a hardness of approximate to 1.3 GPa has been fabricated. The Ca-polyP granules are prone to hydrolytic degradation during in vitro incubation of the cells, suggesting that this property is associated with the observed bioactivity.

  • 出版日期2015-6-1