A new oxidation system for the oxidation of Hantzsch-1,4-dihydropyridines and polyhydroquinoline derivatives under mild conditions

作者：Bai, Cui-Bing; Wang, Nai-Xing^*; Wang, Yan-Jing; Lan, Xing-Wang; Xing, Yalan; Wen, Jia-Long

来源：RSC Advances, 2015, 5(122): 100531-100534.

DOI：10.1039/c5ra20977c

• ONE-POT SYNTHESIS
• HANTZSCH 1,4-DIHYDROPYRIDINES
• 1,3,5-TRISUBSTITUTED PYRAZOLINES
• CATALYTIC AROMATIZATION
• HIGHLY EFFICIENT
• PYRIDINES
• REAGENT
• VINYLARENES
• BROMIDE

A new oxidation system (Na2S2O4/TBHP) to prepare pyridine derivatives has been developed by the oxidation of 1,4-dihydropyridine derivatives and polyhydroquinoline derivatives in good to excellent yields. The procedures of the reaction were green, convenient, mild and easy work-up.

• 出版日期2015
• 单位中国科学院理化技术研究所