Hg2+-selective "turn-on" fluorescent chemodosimeter derived from glycine and living cell imaging

作者：Mahapatra Ajit Kumar^*; Roy Jagannath; Manna Saikat Kumar; Kundu Supratim; Sahoo Prithidipa; Mukhopadhyay Subhra Kanti; Banik Avishek

来源：Journal of Photochemistry and Photobiology A: Chemistry , 2012, 240: 26-32.

DOI：10.1016/j.jphotochem.2012.05.001

• Fluorescent chemodosimeter
• Glycine
• Mercury
• Turn-on fluorescent probes
• Pollen cell

A new nonfluorescent benzthiazole derivative of dithio-N-phthaloylglycine was prepared, and its fluorogenic chemodosimetric behaviors toward transition metal ions were investigated. The dithio-N-phthaloylglycine derivative showed highly Hg2+-selective fluorescence enhancing ("turn-on") properties in 20% aqueous acetonitrile solution (H2O/CH3CN = 80:20, v/v). The chemodosimetric behavior is based on the Hg2+ triggered desulfurization of dithio-N-phthaloylglycine derivative into its oxygen analogue. To observe the cell permeability of 3 into Pollen grains, we also employed it for the fluorescence detection of the changes of intracellular Hg2+ in cultured cells.

• 出版日期2012-7-15