Diffuse Neuroendocrine Hyperplasia with Obliterative Bronchiolitis and Usual Interstitial Pneumonia: An Unusual "Headcheese Pattern" with Nodules

作者：Pietrangeli V; Piciucchi S^*; Tomassetti S; Ravaglia C; Gurioli C; Gurioli Ch; Cavazza A; Dubini A; Poletti V

来源：Lung, 2015, 193(6): 1051-1054.

DOI：10.1007/s00408-015-9817-4

• DIPNECH
• UIP pattern
• Headcheese pattern
• Chromogranin

A 74-year-old non-smoker female presented to our attention with a history of dyspnea and cough. CT scan revealed multiple areas of patchy ground glass attenuation associated to a diffuse mosaic oligoemia. Scattered bilateral subcentimetric pulmonary nodules were also present. Patient underwent a surgical lung biopsy. Specimens showed features of diffuse neuroendocrine hyperplasia, microhoneycombing, fibroblast foci. A final diagnosis of diffuse neuroendocrine hyperplasia with obliterative bronchiolitis and UIP was rendered.

• 出版日期2015-12