A Facile Synthesis of 1,1-Difluoroallenes from Commercially Available 1,1,1-Trifluoro-2-iodoethane

作者：Oh Ken; Fuchibe Kohei; Ichikawa Junji^*

来源：Synthesis, 2011, (6): 881-886.

DOI：10.1055/s-0030-1258438

• fluorinated allenes
• metalation
• carbanions
• elimination
• difluorovinylidenation

1,1-Difluoroallenes are synthesized in good yield via zinc-promoted 1,2-elimination of 3,3-difluoro-2-iodoallylic acetates, which are prepared by the reaction of aldehydes or ketones with 1-iodo-2,2-difluorovinyllithium, generated from commercially available 1,1,1-trifluoro-2-iodoethane.

• 出版日期2011-3