Devastating intracardiac and aortic thrombosis: a case report of apparent catastrophic antiphospholipid syndrome during liver transplantation

作者：Gologorsky Edward^*; Andrews David M; Gologorsky Angela; Sampathi Venkata; Sundararaman Lalitha; Govindaswamy Radhika; Raveh Yehuda; Tzakis Andreas G; Pretto Ernesto A Jr

来源：Journal of Clinical Anesthesia, 2011, 23(5): 398-402.

DOI：10.1016/j.jclinane.2010.07.007

• Antiphospholipid syndrome
• Aortic thrombosis
• Hemostatic therapy
• Intracardiac thrombosis
• Intraoperative pulmonary thromboembolism
• Liver transplantation

Fewer than 80 cases of intracardiac thrombosis and intraoperative pulmonary thromboembolism during liver transplantation have been described. We present a patient who suffered an intraoperative fulminant intracardiac and aortic thrombosis and posthumously was found to have had high anticardiolipin immunoglobulin M concentration and markers of hyperfibrinolysis in preoperatively collected plasma. Hemostatic therapy in the presence of circulating antiphospholipid antibodies and the pathogenesis of a catastrophic antiphospholipid syndrome are discussed.

• 出版日期2011-8