Importance of Surgical Margins in Rectal Cancer

作者：Krishnamurty Devi Mukkai; Wise Paul E

来源：Journal of Surgical Oncology, 2016, 113(3): 323-332.

DOI：10.1002/jso.24136

• rectal cancer
• total mesorectal excision
• distal resection margin
• circumferential resection margin

Distal resection margin (DRM) and circumferential resection margin (CRM) are two important considerations in rectal cancer management. Although guidelines recommend a 2 cm DRM, studies have shown that a shorter DRM is adequate, especially in patients receiving neoadjuvant chemoradiation. Standardization of total mesorectal excision has greatly improved quality of CRM. Although more patients are undergoing sphincter-saving procedures, abdominoperineal resection is indicated for very distal tumors, and pelvic exenteration is often necessary for tumors involving pelvic organs.

• 出版日期2016-3-1