Facile synthesis of novel hybrid POSS biomolecules via "Click" reactions

作者：El Aziz Youssef^*; Mehrban Nazia; Taylor Peter G; Birchall Martin A; Bowen James; Bassindale Alan R; Pitak Mateusz B; Coles Simon J

来源：RSC Advances, 2017, 7(59): 37474-37477.

DOI：10.1039/c7ra07915j

A novel alkyne-terminated cubic-octameric POSS was synthesised in high yield (82-90%). The X-ray crystal structure revealed intra-and intermolecular hydrogen bonding between the amide groups of the arms. Hybrid biomaterials were synthesised in nearly quantitative yields via a click reaction with (i) azido-N-Fmoc-norleucine and (ii) 3'-azido-3'-deoxythymidine.

• 出版日期2017