Superparamagnetic iron oxide nanoparticles for in vivo molecular and cellular imaging

作者：Sharifi Shahriar; Seyednejad Hajar; Laurent Sophie; Atyabi Fatemeh; Saei Amir Ata; Mahmoudi Morteza^*

来源：Contrast Media and Molecular Imaging, 2015, 10(5): 329-355.

DOI：10.1002/cmmi.1638

• cellular imaging
• iron oxide
• molecular imaging
• MRI
• SPIONs
• superparamagnetic nanoparticles

In the last decade, the biomedical applications of nanoparticles (NPs) (e.g. cell tracking, biosensing, magnetic resonance imaging (MRI), targeted drug delivery, and tissue engineering) have been increasingly developed. Among the various NP types, superparamagnetic iron oxide NPs (SPIONs) have attracted considerable attention for early detection of diseases due to their specific physicochemical properties and their molecular imaging capabilities. A comprehensive review is presented on the recent advances in the development of in vitro and in vivo SPION applications for molecular imaging, along with opportunities and challenges.

• 出版日期2015-10