A Review of Cutaneous Drug Eruptions

作者：Ahmed Ammar M^*; Pritchard Sarah; Reichenberg Jason

来源：Clinics in Geriatric Medicine, 2013, 29(2): 527-+.

DOI：10.1016/j.cger.2013.01.008

• Drug eruption
• Adverse cutaneous reaction
• Drug reaction

Cutaneous drug eruptions can range from an asymptomatic rash to a life-threatening emergency. Because of the high frequency, morbidity, and potential mortality associated with drug eruptions, patients with possible drug reactions should promptly be recognized, worked up, and treated. Drug reactions are common in the elderly population due to age-related alterations in metabolism, excretion of medications, and polypharmacy. This review discusses the epidemiology, pathogenesis, clinical presentation, diagnosis, and management of drug eruptions that providers commonly encounter in the care of the geriatric population. An algorithm for an approach to patients with a suspected drug eruption is presented.

• 出版日期2013-5