Advanced jet protocols for directly engineering living cells: a genesis to alternative biohandling approaches for the life sciences

作者：Jayasinghe Suwan N^*

来源：Regenerative Medicine, 2008, 3(1): 49-61.

DOI：10.2217/17460751.3.1.49

• aerodynamically assisted bio-jetting/threading
• bio-electrosprays
• cell electrospinning
• flow cytometry
• living cells
• pressure-assisted cell jetting/spinning
• regenerative and therapeutic medicine

Processing methodologies possessing the ability to directly handle living cells imply tremendous possibilities for a whole host of applications in the regenerative and therapeutic medicinal themes of R&D. Most cell-handling techniques have, in the past, been unearthed in the physical sciences, which have subsequently undergone rapid development for a plethora of applications within the life sciences. in this review, the author wishes to introduce current and swiftly emerging direct cell-handling jet protocols whilst identifying their advantages and disadvantages in comparison to each approach. The article extends to elucidating their applicability for a few life science-based research themes, where these protocols are currently undergoing intense investigation. It is the opinion of this author that these protocols generate a range of opportunities for the life sciences, which have previously not been explored and hence could have an overwhelming affect in a biological and clinical standpoint. These methods and protocols have evidently bridged the physical with the life sciences during this endeavor.

• 出版日期2008-1