Antitubercular dihydroagarofuranoid sesquiterpenes from the roots of Microtropis fokienensis

作者:Chen Jih Jung*; Chou Tsung Hsien; Peng Chien Fang; Chen Ih Sheng; Yang Sheng Zehn
来源:Journal of Natural Products, 2007, 70(2): 202-205.
DOI:10.1021/np060500r

摘要

Four new dihydroagarofuranoid sesquiterpenes (1-4) and a new hydroxybenzylsalicylaldehyde, forkienin (5), together with nine known compounds have been isolated from the roots of Microtropis fokienensis. The structures of the new compounds were determined through analyses of physical data. Compounds 3, 4, 7, and 8 exhibited potent antitubercular activities (MICs <= 26.0 mu M) against Mycobacterium tuberculosis 90-221387 in vitro.

  • 出版日期2007-2