摘要

A stereoselective allylic alkylation of isatin-derived Morita-Baylis-Hillman (MBH) carbonates with nitroalkanes has been developed. In the presence of 10 mol % beta-isocupreidine (beta-ICD), 3,3';-disubstituted oxindoles were prepared with moderate diastereoselectivities and excellent enantioselectivities.

  • 出版日期2012-8-3