AN EFFICIENT SYNTHESIS OF FUNCTIONALIZED CHROMENO[4,3-d]PYRAZOLO[3,4-b]PYRIDINE DERIVATIVES

作者：Lin, Wei^*; Zheng, Yongxiang; Wang, Yazhen; Shi, Daqing^*

来源：Heterocycles, 2016, 92(12): 2235-2243.

DOI：10.3987/COM-16-13567

• ONE-POT SYNTHESIS
• FLUORESCENCE PROPERTIES
• SWITCHING PROPERTIES
• COUMARINS
• DIFFERENTIATION
• CELLS
• ACID

A series of functionalized chromeno[4,3-d]pyrazolo[3,4-b]pyridine derivatives were synthesized via one-pot three-component reaction of salicylaldehydes, 4-hydroxy-6-methyl-2H-pyran-2-one and pyrazol-5-amines catalyzed by L-proline and CuSO4 in ethanol. The structures of all synthesized were identified by their IR, H-1 NMR, C-13 NMR and HRMS analyses, and the structure of compound 4h was confirmed by X-ray diffraction analysis.

• 出版日期2016-12-1
• 单位苏州大学