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摘要
A facile and efficient synthesis of novel 2-amino-6-methyl-4-aryltetrahydronaphthalene derivatives by the reaction of aromatic aldehydes, 4-methylcyclohexanone, and malononitrile in the presence of NaOH and 95% EtOH is reported. This protocol has the advantages of shorter reaction time, mild conditions, and easy work-up. The products were identified by H-1 NMR, IR and HRMS techniques. The reported method is the efficient approach for the synthesis of these compounds.
- 出版日期2013-3
- 单位中国矿业大学（北京）
