A self-assembled monolayer on gold nanoparticles modified electrode for simultaneous determination of isoproterenol and uric acid

作者：Mazloum Ardakani Mohammad^*; Dehghani Firouzabadi Afsaneh; Sheikh Mohseni Mohammad Ali; Benvidi Ali; Mirjalili Bi Bi Fatemeh; Zare Reza

来源：Measurement, 2015, 62: 88-96.

DOI：10.1016/j.measurement.2014.11.020

• Self-assemble
• Gold nanoparticles
• Isoproterenol
• Glassy carbon electrode
• Electrocatalysis

A novel layer-by-layer assembly of gold nanoparticles (AuNPs) and 2-(2,3-dihydroxy phenyl) benzothiazole (DPB) was successfully applied at a glassy carbon electrode (GCE/AuNPs/DPB). At first, AuNPs were deposited on the GCE by chemical and electrochemical methods and then DPB is self-assembled on the Au nanoparticles. This new modified electrode system was characterized by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). GCE/AuNPs/DPB was used for simultaneous determination of isoproterenol (IP) and uric acid (UA). It was observed that an electrode with electrochemical deposited of Au nanoparticles has higher electrocatalytic activity for the oxidation of IP in comparison of the electrode with chemical deposited of Au nanoparticles. Also results show the DPB has a key role in electrocatalysis of IP and in simultaneous determination of procedure because the DPB can catalysis the oxidation of IP via EC' mechanism. Differential pulse voltammetry (DPV) exhibited a linear dynamic range over the concentration range of 0.1-900.0 mu M and a detection limit (3 s) of 82 nM for IP in the optimum conditions. Finally, DPV was used for simultaneous determination of IP and UA and their detection in real samples.

• 出版日期2015-2