摘要

Hybrid systems, and Piecewise Deterministic Markov Processes in particular, are widely used to model and numerically study systems exhibiting multiple time scales in biochemical reaction kinetics and related areas. In this paper an almost sure convergence analysis for numerical simulation algorithms for Piecewise Deterministic Markov Processes is presented. The discussed numerical methods arise through discretising a constructive method defining these processes. The stochastic problem of simulating the random, path-dependent jump times of such processes is reformulated as a hitting time problem for a system of ordinary differential equations with random threshold. Then deterministic continuous methods (methods with dense output) are serially employed to solve these problems numerically. We show that the almost sure convergence rate of the stochastic algorithm is identical to the order of the embedded deterministic method. We illustrate our theoretical findings by numerical examples from mathematical neuroscience, Piecewise Deterministic Markov Processes are used as biophysically accurate stochastic models of neuronal membranes.

  • 出版日期2013-2-1