Maternal health and eating habits: metabolic consequences and impact on child health

作者：Ojha Shalini; Fainberg H Pablo; Sebert Sylvain; Budge Helen; Symonds Michael E^*

来源：Trends in Molecular Medicine, 2015, 21(2): 126-133.

DOI：10.1016/j.molmed.2014.12.005

Apart from direct inheritance and the effects of a shared environment, maternal health, eating habits and diet can affect offspring health by developmental programming. Suboptimal maternal nutrition (i.e., either a reduction or an increase above requirement) or other insults experienced by the developing fetus can induce significant changes in adipose tissue and brain development, energy homeostasis, and the structure of vital organs. These can produce long-lasting adaptations that influence later energy balance, and increase the susceptibility of that individual to obesity and the components of the metabolic syndrome. Studies that elucidate the mechanisms behind these associations will have a positive impact on the health of the future adult population and may help to contain the obesity epidemic.

• 出版日期2015-2