Neck circumference as an independent indicator to non-alcoholic fatty liver disease in non-obese men

作者：Li, Qin; Wang, Ningjian; Han, Bing; Chen, Yi; Zhu, Chunfang; Chen, Yingchao; Xia, Fangzhen; Cang, Zhen; Zhu, Chaoxia; Chen, Chi; Zhai, Hualing; Jiang, Boren; Lin, Dongping; Lu, Yingli^*

来源：Nutrition & Metabolism, 2015, 12(1): 63.

DOI：10.1186/s12986-015-0060-z

• Neck circumference
• NAFLD
• Non-obese

Background : To investigate the relationship of the neck circumference (NC) with non-alcoholic fatty liver disease (NAFLD) in non-obese Chinese population. @@@ Methods: Our data were obtained from a cross-sectional survey on the prevalence of metabolic diseases and risk factors in East China in 2014. Subjects with a BMI >= 18.5 kg/m(2) and < 25 kg/m(2) were considered normal weight. A total of 2668 participants aged 18-89 were identified for analysis. Anthropometric indices, biochemical parameters, clinical characteristics and abdominal ultrasound were measured. Independent predictors of NAFLD were identified by multiple logistic regressions. @@@ Results: The overall prevalence of NAFLD was 10.94 % in this study population and men had a higher prevalence than women (19.89 % vs 7.48 %, P < 0.01). The mean NC was greater in NAFLD subjects compared with other groups in both genders (P < 0.01). NC was correlated to BMI, waist circumference, hip circumference, systolic blood pressure, diastolic blood pressure, insulin, HOMA-IR, triglycerides and ALT, regardless of sex. In the highest quartile of NC levels in men but not in women, the risks were substantially higher for NAFLD [ odds ratio 2.18, (95 % confidence interval 1.16-4.13)] (P < 0.001 for trend) after adjusting for potential confounding factors. @@@ Conclusion: NC was an independent indicator for NAFLD in normal weighted men.

• 出版日期2015-12-30
• 单位上海交通大学