A pilot study of total and allergen-specific IgE serum levels during anestrous, estrous and pregnancy in healthy female dogs

作者：Tarpataki Noemi; Thuroczy Julianna; Fischer Nina; Jacquenet Sandrine; Rostaher Ana; Richard Christelle; Zwickl Lena; Olivry Thierry; Favrot Claude^*

来源：Veterinary Dermatology, 2018, 29(4): 329-+.

DOI：10.1111/vde.12544

Background -Allergen-specific IgE serology is used for the determination of sensitization status in dogs with atopic dermatitis; the influence of the female reproductive cycle on the results of such methods has not been studied in dogs. Objectives -To compare the total and allergen-specific IgE of healthy bitches during anestrous, estrous and pregnancy. Animals -Eight privately owned, healthy bitches. Methods -Total and allergen-specific IgE levels were determined in eight bitches at three different time-points of their reproductive cycle: anestrous, estrous and pregnancy. Results -Total IgE was significantly decreased (median: 74%) in female dogs during pregnancy when compared to anestrous. In 14 of 216 (6%), allergen-specific IgE test results were variably positive and negative at different stages of the reproductive cycle. This variation, however, was not related to changes in total serum IgE levels. Conclusions -Total IgE serum levels are reduced during pregnancy in female dogs. However, results of one allergen-specific IgE test did not appear to be markedly altered by the reproductive cycle in healthy bitches.

• 出版日期2018-8