An Efficient Synthesis of Azetidines with (2-Bromoethyl)sulfonium Triflate

作者:Fritz Sven P; Moya Juan F; Unthank Matthew G; McGarrigle Eoghan M*; Aggarwal Varinder K
来源:Synthesis, 2012, 44(10): 1584-1590.
DOI:10.1055/s-0031-1290951

摘要

Easily accessible arylglycine derivatives were cyclized to azetidines by using commercially available (2-bromoethyl)sulfonium triflate in a simple and mild procedure. The high-yielding reaction has a relatively broad scope and was extended to the synthesis of an oxetane.

  • 出版日期2012-5