Antioxidant and xanthine oxidase inhibitory activities of total polyphenols from onion

作者：Ouyang, Hui^*; Hou, Kun; Peng, Wanxi^*; Liu, Zhenling; Deng, Heping

来源：Saudi Journal of Biological Sciences, 2018, 25(7): 1509-1513.

DOI：10.1016/j.sjbs.2017.08.005

• Total polyphenols
• Onion
• Antioxidant
• Xanthine oxidase
• Inhibitory activities

Onions (Allium cepa L.) comprise a valuable vegetable crop in many countries. Modern scientific research has shown that onions possess many biological activities, including antibacterial, anticancer, hypoglycemic, hypolipidemic, antiplatelet aggregation, and antioxidant activities. The goal of this study was to investigate the impact of total onion polyphenols on antioxidant and xanthine oxidase (XO) inhibitory activities. Total onion polyphenols showed significant antioxidant activity in DPPH, FRAP, and OH-assays (IC50 [mg/mL]), 43.24, 560.61, and 12.97, respectively). In a X/XO system, antioxidant properties of these polyphenols significantly inhibited XO activity (IC50 [mu g/mL], 17.36). These results indicated that total onion polyphenols showed promising antioxidant and anti-gout properties and might be used as potential, natural drugs against oxidative diseases after successful studies in vivo as well as clinical trials.

• 出版日期2018-11
• 单位河南工业大学; 吉首大学