摘要
MASLOW, A. L., X. SUI, N. COLABIANCHI, J. HUSSEY, and S. N. BLAIR. Muscular Strength and Incident Hypertension in Normotensive and Prehypertensive Men. Med. Sci. Sports Exerc., Vol. 42, No. 2, pp. 288-295, 2010. The protective effects of cardiorespiratory fitness (CRF) on hypertension (HTN) are well known: however, the association between muscular strength and incidence of HTN has yet to be examined. Purpose: This study evaluated the strength-HTN association with and without accounting for CRF. Methods: Participants were 4147 men (age = 20-82 yr) in the Aerobics Center Longitudinal Study for whom an age-specific composite muscular strength score was computed from measures of a one-repetition maximal leg and a one-repetition maximal bench press. CRF was quantified by maximal treadmill exercise test time in minutes. Cox proportional hazards regression analysis was used to estimate hazard ratios (HR) and 95% confidence intervals of incident HTN events according to exposure categories. Results: During a mean follow-up of 19 yr, there were 503 incident HTN cases. Multivariable-adjusted (excluding CRF) HR of HTN in normotensive men comparing middle- and high-strength thirds to the lowest third were not significant at 1.17 and 0.84, respectively. Multivariable-adjusted (excluding CRF) HR of HTN in baseline prehypertensive men comparing middle- and high-strength thirds to the lowest third were significant at 0.73 and 0.72 (P = 0.01 each), respectively. The association between muscular strength and incidence of HTN in baseline prehypertensive men was no longer significant after control for CRF (P = 0.26). Conclusions: The study indicated that middle and high levels of muscular strength were associated with a reduced risk of HTN in prehypertensive men only. However, this relationship was no longer significant after controlling for CRF.
- 出版日期2010-2