GREEN METHOD FOR THE SYNTHESIS OF POLYSUBSTITUTED CHROMENE DERIVATIVES IN IONIC LIQUIDS

作者:Zhang, Mei-Mei; Wu, Jian-Rong; Zhou, Jie; Wang, Xiang-Shan*
来源:Synthetic Communications, 2012, 42(4): 599-607.
DOI:10.1080/00397911.2010.528128

摘要

In this article, the same reaction of aromatic aldehyde, malononitrile, and 2-(2,3-dihydrochromen-4-ylidene) malononitrile was performed in ionic liquids of [BMIm]BF4 and [BMIm]Br, resulting in a green synthesis of 6H-benzo[c]chromene-8,8,10(7H)-tricarbonitrile and 6H-benzo[c] chromene-8,10-dicarbonitrile derivatives in good yields. This procedure has the advantages of good yields, one pot, and environmental friendliness.

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