An update on primary progressive aphasia

作者:Rogalski Emily*; Mesulam Marsel
来源:Current Neurology and Neuroscience Reports, 2007, 7(5): 388-392.
DOI:10.1007/s11910-007-0060-0

摘要

Primary progressive aphasia is a neurodegenerative syndrome characterized by a relentless dissolution of language but relative sparing of other cognitive domains during the initial stages of the disease. Substantial progress has been made in understanding the clinical characteristics, imaging, genetics, and neuropathology of this syndrome. This article reviews the clinical criteria for diagnosing primary progressive aphasia and some of the more recent research advances in this field.