摘要

Epistatic miniarray profiling (E-MAP) is powerful for measuring gene biological relevance. However, E-MAP suffers from large number of missing values, and in order to use the E-MAP information more efficiently, the missing values have to be estimated. In this paper, considering advantages and disadvantages of different independent algorithms, we proposed a novel fusion approach based on the high-level diversity to estimate missing values that consists of two global and four local base estimators. Experiment results show our fusion scheme is more effective and robust for the missing value imputations and outperforms all single base algorithms on E-MAP data.

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