科研之友
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摘要
The Pyrin inflammasome guard is disabled if the activity of small cellular GTPase is compromised in response to defects in the mevalonate pathway and is disabled directly by mutations in the gene encoding Pyrin, which results in the interleukin 1 beta (IL-1 beta)-driven autoinflammatory diseases MKD and FMF.
- 出版日期2016-8
- 单位西北大学
