Actin-Based Motility of Burkholderia thailandensis Requires a Central Acidic Domain of BimA That Recruits and Activates the Cellular Arp2/3 Complex

作者：Sitthidet Chayada; Stevens Joanne M; Field Terence R; Layton Abigail N; Korbsrisate Sunee; Stevens Mark P^*

来源：Journal of Bacteriology, 2010, 192(19): 5249-5252.

DOI：10.1128/JB.00608-10

Burkholderia species use BimA for intracellular actin-based motility. Uniquely, Burkholderia thailandensis BimA harbors a central and acidic (CA) domain. The CA domain was required for actin-based motility, binding to the cellular Arp2/3 complex, and Arp2/3-dependent polymerization of actin monomers. Our data reveal distinct strategies for actin-based motility among Burkholderia species.

• 出版日期2010-10