摘要
Anti-idiotype antibody (AId or Ab2) is an antibody raised against the variable region of an original antibody. Based on characters of Aid, it could be used for (i) substituting virulent hapten as standard sample to develop innocuous immunoassay, (ii) designing novel immunoassay model, especially non-competive model, to improve the performance of traditional immunoassay, and (iii) developing multi-target immunoassay. The difficulties inherent in anti-idiotype antibody generation are limiting factors for its wide application, but phage display technology may be a way to circumvent this problem.
- 出版日期2010-9
- 单位西北农林科技大学