Design, Synthesis and Antimicrobial Evaluation of Novel Tricyclic Benzoxazine Fluoroquinolones under Conventional and Microwave Methods

作者:Guruswamy B*; Arul R; Chaitanya M V S R K; Darsi S S Praveen Kumar
来源:Journal of Heterocyclic Chemistry, 2015, 52(2): 532-538.
DOI:10.1002/jhet.2093

摘要

In view of obtaining some potential antimicrobial compounds, we have described synthesis of novel fluoroquinolones bearing 2-(piperidin-4-yl)-1H-benzo[d]imidazole and evaluated for their antimicrobial activity. Alternatively, synthesis of these products was also demonstrated using microwave irradiation technique. The antimicrobial activity of newly synthesized compounds was evaluated against number of microorganisms and the activity is compared with highly active levofloxacin.

  • 出版日期2015-3