DIRECT OXIDATION OF 4-METHYLPYRROLE-2-CARBOXYLATES WITH DDQ IN THE PRESENCE OF A GLYCOL

作者:Takahashi Kana*; Iwamoto Ryoji; Sakata Ryo; Soeta Takahiro; Inomata Katsuhiko; Ukaji Yutaka
来源:Heterocycles, 2012, 86(2): 1031-1038.
DOI:10.3987/COM-12-S(N)126

摘要

Oxidation of 4-methylpyrrole-2-carboxylates with DDQ in the presence of a glycol proceeded smoothly on the methyl group at the C4 position regioselectively to afford the corresponding pyrrole-2,4-dicarboxylates directly. Direct oxidation of a methyl group of 2,4,6-trimethylphenol and 3-methyl-9H-carbazole into carboxylates was also demonstrated.

  • 出版日期2012-12-31