Aerosolized Vaccine as an Unexpected Source of False-Positive Bordetella pertussis PCR Results

作者：Salimnia Hossein; Lephart Paul R; Asmar Basim I; Prebelich Dawn; Paulson Erin; Fairfax Marilynn R^*

来源：Journal of Clinical Microbiology, 2012, 50(2): 472-474.

DOI：10.1128/JCM.01250-11

When 13 of 13 nasal wash specimens from a single pediatrician%26apos;s office tested positive for low quantities of Bordetella pertussis DNA, we suspected prelaboratory contamination. Investigation revealed that Pentacel and Adacel vaccines contain high copy numbers of B. pertussis DNA, which can be aerosolized, causing false-positive B. pertussis PCR results.

• 出版日期2012-2