Novel procedure to enhance PLA surface properties by chitosan irreversible immobilization

作者：Stoleru Elena; Dumitriu Raluca Petronela; Munteanu Bogdanel Silvestru; Zaharescu Traian; Tanase Elisabeta Elena; Mitelut Amalia; Ailiesei Gabriela Liliana; Vasile Cornelia^*

来源：Applied Surface Science, 2016, 367: 407-417.

DOI：10.1016/j.apsusc.2016.01.200

• Poly(lactic acid)
• Chitosan
• Nitrogen plasma
• Gamma radiation
• Electrospinning

A novel two step procedure was applied for poly(lactic acid) (PLA) functionalization consisting in the exposure to cold radiofrequency plasma in nitrogen atmosphere or to gamma irradiation followed by "grafting to" of a chitosan layer using carbodiimide chemistry. The adhesion and stability of the deposited surface layer was assured by plasma/gamma irradiation treatment while the chitosan layer offers antifungal/antibacterial/antioxidant activities. Chitosan with different viscosities/deacetylation degree was deposited by electrospinning or immersion methods. Correlations between rheological behavior of chitosan solutions and chitosan layer deposition conditions are made. The PLA surface properties were investigated by water contact angle measurements, ATR-FTIR spectroscopy, AFM, chemiluminiscence, etc. It has been established that the surface roughness increases direct proportional with cold plasma duration and gamma irradiation dose and further increases by chitosan coating which at its turn depends on chitosan characteristics (viscosity and deacetylation degree) and method of deposition. Nano-fibers with relatively homogeneous and reproducible features are obtained by electrospinning of highly viscous chitosan while with the other two types of chitosan both microparticles and nano-fibers are formed. The chitosan coating obtained by immersion is more homogenous and compact and has a better antibacterial activity than the electrospun layer as fiber meshes.

• 出版日期2016-3-30