Association of Single Nucleotide Polymorphism in Pancreatic Lipase Gene with Growth-Related Traits in Japanese Black Beef Cattle

作者：Tanomura Hideki; Muramatsu Youji; Yamamoto Takuji; Ohta Takeshi; Kose Hiroyuki; Yamada Takahisa^*

来源：Journal of Animal and Veterinary Advances, 2012, 11(9): 1346-1349.

DOI：10.3923/javaa.2012.1346.1349

• Association
• beef cattle
• growth-related trait
• Japanese Black breed
• single nucleotide polymorphism
• PNLIP

Growth performance as well as marbling is the main breeding objectives in Japanese Black cattle, the major beef breed in Japan. Researchers have recently reported that a Single Nucleotide Polymorphism (SNP) referred to as rs41648172 in intron 6 region of the Pancreatic Lipase (PNLIP) gene was associated with marbling in Japanese Black beef cattle with the T allele being associated with a high level of marbling. The PNLIP is known to be involved in the hydrolysis of dietary triglycerides to fatty acids which is essential for the intestinal absorption of long-chain triglyceride fatty acids. Thus, the PNLIP was considered as a functional candidate for the gene responsible for growth performance. In this study, researchers analyzed the effect of the PNLIP rs41648172 SNP genotypes on the growth-related traits in Japanese Black beef cattle. The SNP was associated with carcass weight, rib eye area, rib thickness and daily gain in the experiment using 367 paternal half-sib progeny steers from a sire homozygous for C allele at the rs41648172 in Japanese Black beef cattle. The SNP was also associated with carcass weight, rib eye area and daily gain in the experiment using 587 paternal half-sib progeny steers from a sire homozygous for T allele at the rs41648172 in Japanese Black beef cattle. These findings suggest possible effect of the rs41648172 on the growth-related traits in Japanese Black beef cattle. The PNLIP SNP polymorphism may be useful for effective marker-assisted selection to increase the beef productivity in Japanese Black beef cattle.

• 出版日期2012