科研之友
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摘要
The azanucleosides are nucleoside analogues where the furanose ring is replaced by a nitrogen-containing ring or chain. Many azanucleosides are potent antiviral, anticancer and antimicrobial agents, or serve as valuable components of oligonucleotides with improved stability, binding or hybridization properties. Therefore, the development of new analogues is a very active area in medicinal and synthetic chemistry. Their synthesis and their interesting biological properties are discussed in this microreview.
- 出版日期2014-4
