Blood selenium concentration in a selected population of children inhabiting industrial regions in Upper Silesia (Poland)

作者：Gac Pawel; Pawlas Natalia; Poreba Rafal^*; Poreba Malgorzata; Prokopowicz Adam; Pawlas Krystyna

来源：Environmental Toxicology and Pharmacology, 2012, 34(2): 528-536.

DOI：10.1016/j.etap.2012.06.005

• Blood selenium concentration
• Children

Purpose: Present study aimed at determining blood selenium concentration (Se-B) in a selected population of children inhabiting industrial regions.
Methods: The studies were conducted on a group of 267 children inhabiting industrial regions in Upper Silesia (Poland). Determination of Se-B was performed using hydride generation atomic absorption technique.
Results: In the studied group of children mean Se-B amounted to 76.75 +/- 12.52 mu g/L. Only in 38.20% of studied children the estimated Se-B could be regarded as an optimal. Children with underweight (BMI < 15th centile) manifested a significantly lower Se-B than children with BMI within the normal range (BMI 15-85th centile). In the entire study group of children a significant positive linear correlation was disclosed between BMI and Se-B (r = 0.16, p<0.05). Regression analysis demonstrated that in the studied subgroup of children (with normal height, body mass and BMI) a higher BMI represented an independent factor of Se-B increase and a more pronounced age an independent factor of Se-B decrease. Moreover, maternal education represented an independent factor of Se-B increase in the studied group of children (with normal height, body mass and BMI).
Conclusions: Se-B in the studied group children from industrial area in Upper Silesia corresponded with the lower range of blood selenium concentrations noted in recent years in other populations. A negative relationship was documented between age and Se-B and a positive relationship between BMI of a child and maternal education on one hand and Se-B of a child on the other.

• 出版日期2012-9