Urinary Tract Infection Pathogenesis: Host Factors

作者：Stapleton Ann E^*

来源：Infectious Disease Clinics of North America, 2014, 28(1): 149-+.

DOI：10.1016/j.idc.2013.10.006

• Modifiable host factors
• Nonmodifiable host factors
• Sexual intercourse
• Estrogen status
• Urogenital microbiota
• Female gender

Clinically, host factors in the pathogenesis of urinary tract infection (UT!) may be considered as modifiable (eg, behaviors associated with increased risk of UTI, anatomic and functional problems of the urinary tract) and thus potentially amenable to a change in patient behavior or treatment approach, or as intrinsic and nonmodifiable host factors that neither the patient nor the clinician can influence (eg, gender and genetic influences associated with UTI). Although considering nonmodifiable host factors may be discouraging to patients and clinicians at present, some genetic associations have the potential for future predictive value and may interface with future treatments.

• 出版日期2014-3